ANTIBAKTERIAL FAOLLIKKA EGA BO‘LGAN YANGI ORGANIK ASOSLI, XONA HARORATIDA FOSFORLANUVCHI MATERIALLARNING FUNKSIONAL XOSSALARI
DOI:
https://doi.org/10.5281/zenodo.20735652Keywords:
organik fosforlanish, xona harorati (RTP), rigid mikromuhit, vodorod bog‘lanishi, singlet-triplet konversiyasi, Staphylococcus aureus, Escherichia coli, faol kislorod shakllari (ROS), bakteritsid effekt, yashil kimyo.Abstract
Ushbu tadqiqot ishida yashil kimyo prinsiplari asosida, atrof-muhit uchun xavfsiz gidrotermal usul yordamida
ham xona haroratida uzoq muddatli fosforlanish (RTP), ham yuqori antibakterial faollik xususiyatiga ega bo‘lgan yangi
organik asosli gibrid kompozit materiallar sintez qilingan va ularning funksional xossalari tizimli ravishda tadqiq etilgan.
Fizik-kimyoviy tahlillar (FTIR, XRD, SEM, EDX) matritsa zanjirlari va mehmon molekulalari o‘rtasida zich molekulalararo
vodorod bog‘lanishlari tarmog‘i hosil bo‘lganligini va bu tizim triplet eksitonlarining issiqlik hamda kislorod hisobiga radiatsiyasiz
so‘nishini samarali to‘suvchi rigid “molekulyar qafas” vazifasini bajarganligini ko‘rsatdi. Optik o‘lchovlar natijasida
materialning atmosfera havo muhitida yuqori darajadagi [2,48 sekund] davom etuvchi yorqin fosforlanish xususiyatiga
ega ekanligi aniqlangan. Mikrobiologik sinovlar sintez qilingan gibrid material sirt zaryadlarining elektrostatik ta’siri va faol
kislorod shakllari (ROS) hisobiga Staphylococcus aureus va Escherichia coli patogen bakteriyalarining o‘sishini 24 soat
ichida mos ravishda 94,6% va 88,2% gacha sezilarli darajada ingibirlash imkoniyatiga ega bo‘lgan bakteritsid samaradorligini
namoyon etdi. Olingan natijalar ushbu materiallardan tibbiyotda o‘z-o‘zini sterillovchi “aqlli” qoplamalar va oziq-ovqat
xavfsizligida intellektual qadoqlash tizimlarini yaratishda foydalanishning keng amaliy imkoniyatlarini ochib beradi.
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